Comprehensive Introduction
2-Methyltetrahydrofuran (2-MeTHF) is a new generation of bio-based solvents derived from renewable, non-edible biomass sources such as corn cobs. With its transparent appearance and mild etheric odour, 2-MeTHF is distinguished by its ability to replace traditional petroleum solvents such as tetrahydrofuran (THF) and methylene chloride without compromising performance. In the industrial and pharmaceutical sectors, 2-MeTHF is well known for its compatibility with organometallic reagents and catalytic systems. 2-MeTHF plays a vital role in complex synthesis processes, especially those involving high-value active pharmaceutical ingredients (APIs), where solvent reliability and purity are essential.
Whether for lab-scale innovation or full-scale production, 2-MeTHF offers future-proof solutions for companies that want to combine operational performance with sustainability goals.
Product Details
| Product Name | 2-methyltetrahydrofuran CAS 96-47-9 |
| CAS NO. | 96-47-9 |
| Key words | 2-Methyltetrahydrofuran, 2-MeTHF for pesticides, 2-methyltetrahydrofuran |
| Molecular Formula | C5H10O |
| HS Number | 2932190090 |
| Structural Formula | ![]() |
Specification
|
Items |
Standard |
|
Appearance |
Colourless, transparent liquid |
|
Source |
Biomass(corn cob) |
|
Purity (%) |
≥99.5 |
|
Moisture (%) |
≤ 0.03 |
|
Density (g/cm³) |
0.86 |
|
Boiling point |
78-80 |
Usage & Core function of 2-methyltetrahydrofuran
As a high-performance, environmentally friendly solvent, 2-methyltetrahydrofuran shows excellent performance in organometallic reactions, Grignard reagent systems, petrochemical processes and various catalytic transformations. Its high boiling point, low water solubility and good thermal stability not only facilitate precise control of the reaction, but also facilitate efficient product separation and solvent recovery. For companies seeking to improve production efficiency and reduce overall costs, this is a preferred solvent that combines performance and economy.
In pharmaceutical manufacturing, customers are highly focused on key factors such as 'biobased origin' and 'low toxicity'. Our 2-methyltetrahydrofuran, made from renewable resources, is both environmentally friendly and process-adaptable, especially for companies engaged in the synthesis of high-value-added active pharmaceutical ingredients (APIs), meeting compliance requirements and contributing to a green and sustainable supply chain.
Advantage of 2-methyltetrahydrofuran on the Market
1. Bio-Based & Sustainable
Sourced from renewable biomass, 2-MeTHF aligns with global trends toward green chemistry and sustainable manufacturing, offering an environmentally friendly alternative to petroleum-derived solvents.
2.Regulatory Compliance
Its lower toxicity and favorable safety profile help manufacturers meet stringent environmental and health regulations (e.g., ICH, REACH), reducing compliance risks.
3.Superior Solvent Performance
Compared to traditional solvents like THF or dichloromethane, 2-MeTHF offers a higher boiling point, lower water miscibility, and excellent solubility for a wide range of compounds, making it ideal for advanced pharmaceutical synthesis.
4.Efficient Solvent Recovery
Its hydrophobic nature and thermal stability enable easier separation and recycling, lowering operational costs and solvent waste in large-scale production.
5.Wide range of application scenarios, market potential continues to expand
In addition to mature applications in the pharmaceutical industry, 2-MeTHF has also shown good suitability in the fields of fine chemicals, agrochemical intermediates, and material science, gradually expanding the boundaries of its commercial applications.
Production Capacity

Full-Cycle Safety Certifications

Recommended Product Applications
High-value intermediate synthesis
Pharmaceuticals and pesticides
Fragrances
New energy materials
Environmentally friendly polymers
Packing
Sealed in: 180kg Drum or 20mt ISO tank
If you require samples or small quantities of 2-Methyltetrahydrofuran (2-MeTHF), we offer a variety of packaging options to suit your needs.

FAQ
Q: How does 2-MeTHF perform in organometallic reactions?
A: 2-MeTHF is highly effective in organometallic reactions such as Grignard and lithiation, offering better stability, solubility, and reaction control compared to traditional solvents.
Q: What are the benefits of using 2-MeTHF in large-scale production?
A: Its high boiling point, low water solubility, and ease of recovery reduce solvent loss, lower operational costs, and improve process efficiency in industrial-scale synthesis.
Q: Why choose Shandong Yino?
A: 1. Stable supply and quality
The raw materials of 2-methyltetrahydrofuran, furfural and 2-methylfuran, are our commercial products. We guarantee a stable supply (annual output of 15,000 tons, the world's largest 2-methyltetrahydrofuran producer); self-production of raw materials also allows us to better control the quality stability.
2. The quality control department is independent of the factory and strictly controls the quality
3. The business covers the world, there are agents in ports around the world, and various trade terms are acceptable
4. Focus on environmental protection and sustainable development
There is a full set of waste gas, wastewater, and waste residue treatment, and recycling them to generate electricity.
Specification
|
Items |
Standard |
|
Appearance |
Colourless, transparent liquid |
|
Source |
Biomass(corn cob) |
|
Purity (%) |
≥99.5 |
|
Moisture (%) |
≤ 0.03 |
|
Density (g/cm³) |
0.86 |
|
Boiling point |
78-80 |
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