Comprehensive Overview
Pharmaceutical Intermediate Tetrahydrofurfuryl Alcohol (THFA) (CAS No. 97-99-4), also referred to as Tetrahydrofuran-2-ylmethanol,2-hydroxymethyltetrahydrofuran, and Tetrahydro-2-furancarbinol, is a highly valuable compound in active pharmaceutical ingredient (API) manufacturing. Sourced from renewable furfural, THFA combines chemical functionality with low toxicity and biodegradability, making it a preferred choice in modern drug development processes.
With excellent solvating ability and high purity, THFA is widely used as a building block or reaction medium in the synthesis of key intermediates. Its mild odor and compatibility with various organic compounds contribute to its utility in both large-scale synthesis and laboratory research.
Product Details
| Product Name | Tetrahydrofurfuryl alcohol CAS 97-99-4 |
| CAS NO. | CAS 97-99-4 |
| Key words | Tetrahydrofuran-2-yl methanol, THFA, 2-hydroxy- methyltetrahydrofuran, tetrahydro-2-furancarbinol, tetrahydro-2-furylmethanol |
| Molecular Formula | C5H10O2 |
| HS Number | 29321300 |
| Structural Formula |  |
| Quality standard for Tetrahydrofurfuryl alcohol CAS 97-99-4 | |
| Appearance | Colourless to light yellow clear liquid. |
Specification
|
Items |
Standard |
|
Appearance |
colourless to light-yellow liquid |
|
Purity (%) |
≥99.0 |
|
Moisture (%) |
≤ 0.10 |
|
Density (g/cm³) |
1.051-1.054 |
|
Furfuryl alcohol(%) |
≤0.08 |
|
APHA colour |
≤ 20 |
Usage & Core function of Tetrahydrofurfuryl alcohol CAS 97-99-4
Tetrahydrofurfuryl Alcohol serves as a multi-purpose intermediate and is commonly used in high-value sectors where precision, purity, and consistency are essential.
Typical Application Areas:
- API Synthesis:
Acts as a precursor or solvent in the production of pharmaceutical compounds, ensuring process reliability and high product yield.
- Agrochemical Intermediates:
Applied in the formulation of crop protection products and herbicide ingredients requiring precise molecular structures.
- Research and Development:
Employed in chemical laboratories for reactions needing a stable, low-toxicity medium
- Polymer and Resin Production:
While primarily a pharma intermediate, it also finds use in polyurethane and polyester synthesis due to its functional groups.
Production Capacity
Full-Cycle Safety Certifications
Recommended Product Applications
Coatings
Plastics
Pharmaceuticals
Agrochemicals
Fragrances
Packing
1. 220kg/plastic drum&iron drum,20"fcl contains 80drums totally 17.6mts with(without) pallet;
2. 20mts/ISO Tank.
FAQ
Q: Why is Tetrahydrofurfuryl Alcohol used in pharmaceutical synthesis?
A: Its high purity, reactivity, and biocompatibility make it ideal for reactions requiring stringent quality control, especially in regulated environments.
Q: Is THFA suitable for green chemistry in pharma?
A: Yes. As a biomass-derived solvent/intermediate, it supports eco-friendly synthesis and aligns with regulatory trends promoting sustainable practices in drug manufacturing.
Specification
|
Items |
Standard |
|
Appearance |
colourless to light-yellow liquid |
|
Purity (%) |
≥99.0 |
|
Moisture (%) |
≤ 0.10 |
|
Density (g/cm³) |
1.051-1.054 |
|
Furfuryl alcohol(%) |
≤0.08 |
|
APHA colour |
≤ 20 |
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